9-{[1(R)-acetoxymethyl-2(S)-cyclohex-4-enyl]methyl}2-amino-6-benzyloxypurine → HCID 136395916, compound

Participants

Reaction Steps

A suspension of 9-{[1(R)-acetoxymethyl-2(S)-cyclohex-4-enyl]methyl}2-amino-6-benzyloxypurine (0.75 mmol), ethanol (5 mL) and a catalytic amount of 10% Pd/C was stirred under a hydrogen balloon for 3 hours. The reaction was filtered and concentrated to yield the desired compound. 1HNMR (500 mHz, d6DMSO): 10.80 ppm (bs, 1H); 7.65 (s, 1H); 6.48 (s, 2H); 4.15-3.88 (m, 4H); 2.23 (bs, 1H); 2.01 (s, 3H); 1.92 (m, 1H); 1.68-1.15 (m, 8H).

Provenance & Evidence