HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 131720162, compound → H-Asp(OtBu)-Ser(tBu)-OtBu
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 131720162 | HCID 131720162 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | H-Asp(OtBu)-Ser(tBu)-OtBu | HCID 131720161 | 91% |
Reaction Steps
1.9 g of Z-Asp(OtBu)-Ser(tBu)-OtBu are hydrogenated in 100 ml of methanol in the presence of 0.1 g of Pd/C 10%. After the theoretical amount of hydrogen has been taken up the mixture is filtered and the filtrate is evaporated to dryness. Chromatography on silica gel with methylene chloride/MeOH (98:2) gives 1.28 g (91%) of H-Asp(OtBu)-Ser(tBu)-OtBu, MS: 389 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05663297 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-d81749011f0d4862a65430206ca5b6cc |
| Source note | uspto-grants-1997_09 |