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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1376699Generated: October 31, 2026

Hydrochloric Acid → 2-(4-Nitroanilino)ethanol

https://huagongshe.com/reaction/1376699

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantAcetanilideHCID 904—
ReactantSulfuric acid, mixt. with nitric acidHCID 71777668—
Product2-(4-Nitroanilino)ethanolHCID 266154—

Reaction Steps

The above acetanilide (11.05 g, 0.05 mol) is treated with nitric acid-sulfuric acid mixture and hydrolyzed with 2.5N hydrochloric acid, in the manner as set forth subsequently herein in Example 11, to provide N-(2-hydroxyethyl)-4-nitrobenzenamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05663308
Source datasetuspto-grants-1997_09
ORD IDord-d1f5378502d847bf8ae652be3e498044
Source noteuspto-grants-1997_09