Sodium borohydride → HCID 54256453, compound

HRID 1376721Notes

Reaction equation

HRID 1376721 reaction equation
[CH:1]1([N:4]2[C:13]3[C:8](=[CH:9][C:10]([F:15])=[C:11]([F:14])[CH:12]=3)[C:7](=[O:16])[CH:6]=[C:5]2C(O)=O)[CH2:3][CH2:2]1.[BH4-].[Na+]>>[CH:1]1([N:4]2[C:13]3[C:8](=[CH:9][C:10]([F:15])=[C:11]([F:14])[CH:12]=3)[C:7](=[O:16])[CH2:6][CH2:5]2)[CH2:3][CH2:2]1

Participants

3

Reactant 2

HCID 4311764Sodium borohydrideHCID 54030295HCID 54030295, compound

Product 1

HCID 54256453HCID 54256453, compoundYield 86%

Procedure

1-Cyclopropyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline carboxylic acid(20 g) and sodium borohydride(11.5 g) were reacted in the same method as described in Preparation 1-A to give the yellow above-indicated compound(12 g).

Sources & evidence

ORD record
ord-ff8c4ed0fd9840b6ab3e83cf80202fef
Source dataset
uspto-grants-1997_09
Patent number
US05663331

Reaction notes

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