Sodium borohydride → HCID 10856761, compound

HRID 1376723Notes

Reaction equation

HRID 1376723 reaction equation
[CH2:1]([N:3]1[C:12]2[C:7](=[CH:8][C:9]([F:14])=[C:10]([F:13])[CH:11]=2)[C:6](=[O:15])[CH:5]=[C:4]1C(O)=O)[CH3:2].[BH4-].[Na+]>>[CH2:1]([N:3]1[C:12]2[C:7](=[CH:8][C:9]([F:14])=[C:10]([F:13])[CH:11]=2)[C:6](=[O:15])[CH2:5][CH2:4]1)[CH3:2]

Participants

3

Reactant 2

HCID 4311764Sodium borohydrideHCID 54003184HCID 54003184, compound

Product 1

HCID 10856761HCID 10856761, compoundYield 80%

Procedure

1-Ethyl-6,7-difluoro-1,4-dihydro-4-oxoquinoline carboxylic acid(20 g) and sodium borohydride(12 g) were reacted in the same method as described in Preparation 1-A to give the bright-yellow above-indicated compound(11 g).

Sources & evidence

ORD record
ord-8e163c9c42054d90a67065aa8983fd1a
Source dataset
uspto-grants-1997_09
Patent number
US05663331

Reaction notes

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