HRID1376828

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CCC1SCC2C(NC(=O)C(=NOC)c3csc(NC(c4ccccc4)(c4ccccc4)c4ccccc4)n3)C(=O)N2C1(O)C(=O)OC(C)(C)C

HCID54386289

未命名化合物

HCID86751199

未命名化合物

PRODUCTS

生成物

结构：CCC1=C(C(=O)OC(C)(C)C)N2C(=O)C(NC(=O)C(=NOC)c3csc(NC(c4ccccc4)(c4ccccc4)c4ccccc4)n3)C2CS1

HCID54219298

未命名化合物

收率 32.5%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

Using the procedure of Example 1, 560 mg of diphosphorous tetraiodide, 4.5 ml of pyridine and 394 mg of the product of Step B were reacted to obtain 125 mg of 1,1-dimethylethyl 7-[2-(2-tritylaminothiazol-4-yl)-2-methoxyimino-acetamido]-8-oxo-3-ethyl-4-thia-1-azabicyclo[4,2,0]oct-2-ene-2-carboxylate.

WORKUP

后处理

customwere reacted

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-624e556ec2b642bf9be0ad743b46e01e
来源数据集: uspto-grants-1997_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05663164
来源说明: uspto-grants-1997_09

反应 SMILES

P(I)(I)OP(I)I.[C:8]([NH:27][C:28]1[S:29][CH:30]=[C:31]([C:33](=[N:56][O:57][CH3:58])[C:34]([NH:36][CH:37]2[C:44](=[O:45])[N:43]3[CH:38]2[CH2:39][S:40][CH:41]([CH2:54][CH3:55])[C:42]3(O)[C:46]([O:48][C:49]([CH3:52])([CH3:51])[CH3:50])=[O:47])=[O:35])[N:32]=1)([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)([C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>N1C=CC=CC=1>[C:8]([NH:27][C:28]1[S:29][CH:30]=[C:31]([C:33](=[N:56][O:57][CH3:58])[C:34]([NH:36][CH:37]2[C:44](=[O:45])[N:43]3[CH:38]2[CH2:39][S:40][C:41]([CH2:54][CH3:55])=[C:42]3[C:46]([O:48][C:49]([CH3:52])([CH3:50])[CH3:51])=[O:47])=[O:35])[N:32]=1)([C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1)([C:15]1[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1)[C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1