HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isoamyl Nitrite → 1H-Pyrazol-5-amine,1-methyl-4-nitro-(9CI)
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isoamyl Nitrite | HCID 8053 | — |
| Reactant | 2-Methyl-2H-pyrazol-3-ylamine | HCID 136927 | — |
| Product | 1H-Pyrazol-5-amine,1-methyl-4-nitro-(9CI) | HCID 588382 | — |
Reaction Steps
Total yields of up to 46 percent are obtained when the 5-amino-1-methylpyrazole is converted with isoamyl nitrite to produce 5-amino-1-methyl-4-nitropyrazole and reduced with zinc(II)chloride to give 4,5-diamino-1-methylpyrazole according to H. Dorn, et al., Liebigs Ann. Chem. 717, p. 118 (1968).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05663366 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-7210d6ee4bb14b728aa00fa361390187 |
| Source note | uspto-grants-1997_09 |