HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Acetyl-6-fluorobenzoic acid → HCID 178466551, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Acetyl-6-fluorobenzoic acid | HCID 15278686 | — |
| Reactant | 3-Amino-1-(3,5-difluorophenyl)urea | HCID 15278687 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 178466551 | HCID 178466551 | — |
Reaction Steps
3 g of 6-fluoro-2-acetyl benzoic acid and 3 g of 4-(3,5-difluorophenyl)semicarbazide are mixed in 20 ml of methanol and heated until clear. The solution is then stirred at R.T. for 24 hr. A white solid forms which is filtered and dried in vacuum at 60° to yield the title product m.p. 227° (decomp.). The corresponding sodium salt is made by reaction of the free acid with 25% sodium methoxylate/methanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05665674 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-6bb1f3a1b5ab4d0682c4474ce8e85626 |
| Source note | uspto-grants-1997_09 |