HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Iodide → HCID 23294184, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Iodide | HCID 5238 | — |
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 2-Tert-butoxycarbonylamino-6-methylbenzylchloride | HCID 14368482 | — |
| Reactant | HCID 21873989 | HCID 21873989 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 23294184 | HCID 23294184 | — |
Reaction Steps
The title compound is prepared according to the procedure described for example 7 starting from 8-amino-3-formyl-2-methylimidazo[1,2-a]pyridine (4.0 g), 2-tert-butoxycarbonylamino-6-methylbenzylchloride (7.0 g), sodium iodide (4.1 g) and sodium carbonate (6.1 g) in acetone (250 ml). Purification by chromatography on silica gel (toluene/dioxane 9:1 as eluent) and crystallization from diisopropyl ether yield 7.3 g (81%) of m.p. 210°-212° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05665730 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-3afafba3e027475987a3099139328cc9 |
| Source note | uspto-grants-1997_09 |