Hydrochloric Acid → HCID 178441671, compound

Participants

Reaction Steps

150 mg (0.23 mmole) of the compound obtained in step 1 of Example 1 was dissolved in 3 ml of tetrahydrofuran and to the resulting solution was added 2 ml of aqueous 4N HCl solution. The resultant was stirred for 15 hours at room temperature, neutralized with aqueous 4N NaOH solution, concentrated under reduced pressure and purified with silica gel column chromatography to obtain 101 mg of the title compound (yield 83%).

Provenance & Evidence