2-((2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)-N-methylbenzamide → Bis(2-methoxyethyl) (3-methoxy-4-{[4-{[2-(methylcarbamoyl)phenyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}benzyl)phosphonate

HRID 137755Notes

Reaction equation

HRID 137755 reaction equation
[CH3:23][O:24][CH2:25][CH2:26][O:27][P:28]([O:29][CH2:30][CH2:31][O:32][CH3:33])(=[O:34])[CH2:35][c:36]1[cH:37][c:38]([O:43][CH3:44])[c:39]([NH2:42])[cH:40][cH:41]1.[Cl:1][c:2]1[n:3][cH:4][c:5]([C:19]([F:20])([F:21])[F:22])[c:6]([NH:8][c:9]2[c:10]([C:11](=[O:12])[NH:13][CH3:14])[cH:15][cH:16][cH:17][cH:18]2)[n:7]1>>[c:2]1([NH:42][c:39]2[c:38]([O:43][CH3:44])[cH:37][c:36]([CH2:35][P:28]([O:27][CH2:26][CH2:25][O:24][CH3:23])([O:29][CH2:30][CH2:31][O:32][CH3:33])=[O:34])[cH:41][cH:40]2)[n:3][cH:4][c:5]([C:19]([F:20])([F:21])[F:22])[c:6]([NH:8][c:9]2[c:10]([C:11](=[O:12])[NH:13][CH3:14])[cH:15][cH:16][cH:17][cH:18]2)[n:7]1

Participants

3

Reactant 2

HCID 866338612-((2-Chloro-5-(trifluoromethyl)pyrimidin-4-yl)amino)-N-methylbenzamideHCID 86654042Bis(2-methoxyethyl)(4-amino-3-methoxybenzyl)phosphonate

Product 1

HCID 58292963Bis(2-methoxyethyl) (3-methoxy-4-{[4-{[2-(methylcarbamoyl)phenyl]amino}-5-(trifluoromethyl)pyrimidin-2-yl]amino}benzyl)phosphonate

Sources & evidence

ORD record
ord-c321d33e500a43adaa47bbc6a86bdb72
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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