HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dichloromethane → HCID 22914701, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 54546582 | HCID 54546582 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 22914701 | HCID 22914701 | 90% |
Reaction Steps
4-(N-t-Butoxycarbonyl-4-piperidinyloxy)-2-chlorobenzoic acid methyl ester was saponified to the carboxylic acid with aqueous NaOH in MeOH using the procedure of Step 3 in Example 11. 4-(N-t-Butoxycarbonyl-4-piperidinyloxy)-2-chlorobenzoic acid was obtained as a foam by evaporation of a DCM solution under reduced pressure (90% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05665719 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-488afa95e88a4eb0b8aabd222504832e |
| Source note | uspto-grants-1997_09 |