Sodium Hydroxide → HCID 22914670, compound

HRID 1377693Notes

Reaction equation

HRID 1377693 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:13][CH2:12][CH:11]([NH:14][C:15]2[CH:19]=[CH:18][S:17][C:16]=2[C:20]([O:22]C)=[O:21])[CH2:10][CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].[OH-].[Na+]>>[C:1]([O:5][C:6]([N:8]1[CH2:9][CH2:10][CH:11]([NH:14][C:15]2[CH:19]=[CH:18][S:17][C:16]=2[C:20]([OH:22])=[O:21])[CH2:12][CH2:13]1)=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 2

HCID 14798Sodium HydroxideHCID 22914655HCID 22914655, compound

Product 1

HCID 22914670HCID 22914670, compound

Procedure

The product from Step 1 is saponified with aqueous NaOH to give 3-(1-tert-butyloxycarbonylpiperidin-4-ylamino)thiophene-2-carboxylic acid.

Sources & evidence

ORD record
ord-1eec0c7aa3b34c978afcacd0da327731
Source dataset
uspto-grants-1997_09
Patent number
US05665719

Reaction notes

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