HCID 22915413, compound → HCID 22915420, compound

Participants

Reaction Steps

To a stirred suspension of 3-[5-(4-fluorophenoxy)-2-furyl]-4,4-dichloro-2-cyclobutenone (6.4 g; 20 mM) in acetic acid (25 ml) was added zinc dust (6.5 g; 100 mM) at room temperature. After stirring for 2 hr, zinc was filtered off. The filtrate was evaporated in vacuo. The residue was purified by flash column (SiO2) eluting with ethyl acetate-n-hexane (1:7) to give 2.2 g (yield 45%) of subtitle compound.

Provenance & Evidence