HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 4'-(6-Hydroxyhexyloxy)-4-cyanobiphenyl
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 6-Bromo-1-hexanol | HCID 77970 | — |
| Reactant | 4'-Hydroxy-4-biphenylcarbonitrile | HCID 140610 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 4'-(6-Hydroxyhexyloxy)-4-cyanobiphenyl | HCID 11173950 | 48% |
Reaction Steps
Using 5 g (25.6 mmol) of 4-cyano-4'-hydroxybiphenyl, 85 ml of acetonitrile, 4.63 g (25.6 mmol) of 6-bromohexanol and 7.09 g (51.2 mmol) of anhydrous potassium carbonate, synthetic treatment was carried out in the same manner as in Example 2. The obtained gray powder was recrystallized from methanol to obtain 3.6 g (yield: 48%) of 4-cyano-4'-(6-hydroxyhexyloxy)biphenyl (24) as a colorless powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05665856 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-ffd2a9acf340421ab1283926cc8c3e97 |
| Source note | uspto-grants-1997_09 |