Ammonia → HCID 10587235, compound

HRID 1377915Notes

Reaction equation

HRID 1377915 reaction equation
[C:1]1([C:7]2[CH:18]=[CH:17][C:10]([O:11][CH2:12][CH2:13][C:14](O)=[O:15])=[CH:9][CH:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C1(C2C=CC([O:29]C(C)CC(O)=O)=CC=2)C=CC=CC=1.[NH3:38]>>[C:1]1([C:7]2[CH:18]=[CH:17][C:10]([O:11][CH2:12][CH2:13][C:14]([NH:38][OH:29])=[O:15])=[CH:9][CH:8]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 3

HCID 222AmmoniaHCID 16776070HCID 16776070, compoundHCID 22915495HCID 22915495, compound

Product 1

HCID 10587235HCID 10587235, compound

Procedure

The desired compound was prepared according to the method of Example 1, step 3, except substituting 3-(4-phenylphenoxy)propionic acid, prepared as in step 1, for 3-(4-phenylphenoxy)butanoic acid. 1H NMR (DMSO-d6) δ 2.44 (t, 2H, J=7 Hz), 4.22 (t, 2H, J=7 Hz), 7.01 (d, 2H, J=6 Hz), 7.31 (t, 1H, J=5 Hz), 7.42 (t, 2H, J=5 Hz), 7.61 (m, 4H), 8.88 (bds, 1H, 10.53 (s, 1H). MS (DCI/NH3) 275 (M+NH4+, 100). Anal. Calcd for C15H15NO3 ·0.25 H2O: C, 68.82; H, 5.36; N, 5.70. Found: C, 68.78; H, 5.27; N, 5.18.

Sources & evidence

ORD record
ord-dae62ff68e8e4162bdc31ce24be63f6b
Source dataset
uspto-grants-1997_09
Patent number
US05665777

Reaction notes

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