Sodium ion → 5-Bromo-2-(4-trifluoromethylphenyl)pyrimidine

HRID 137808Notes

Reaction equation

HRID 137808 reaction equation
[Br:1][c:2]1[cH:3][n:4][c:5]([I:8])[n:6][cH:7]1.[C:22](=[O:23])([O-:24])[O-:25].[F:9][C:10]([c:11]1[cH:12][cH:13][c:14]([B:17]([OH:18])[OH:19])[cH:15][cH:16]1)([F:20])[F:21].[Na+:26].[Na+:27]>>[Br:1][c:2]1[cH:3][n:4][c:5](-[c:14]2[cH:13][cH:12][c:11]([C:10]([F:9])([F:20])[F:21])[cH:16][cH:15]2)[n:6][cH:7]1

Participants

5

Reactant 4

HCID 923Sodium ion2×HCID 19660Carbonate IonHCID 27343894-(Trifluoromethyl)phenylboronic acidHCID 70066515-Bromo-2-iodopyrimidine

Product 1

HCID 232970515-Bromo-2-(4-trifluoromethylphenyl)pyrimidine

Sources & evidence

ORD record
ord-ecfcf694d7404fe287027045c16e61b3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…