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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1378317Generated: October 25, 2026

Phenol → 2-Naphthyloxy proline amide

https://huagongshe.com/reaction/1378317

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenolHCID 996—
Reactant2-NaphtholHCID 8663—
Reactantn-t-Butyl-4(s)-phenoxy-l-prolineamide trifluoroacetic acid saltHCID 22862000—
Product2-Naphthyloxy proline amideHCID 22861993—

Reaction Steps

Following substantially the same procedure for synthesizing N-t-butyl-4(S)-phenoxy-L-prolineamide trifluoroacetic acid salt as outlined in Example 1, Steps 6 through 8, but substituting 2-naphthol for the phenol used therein, the 2-naphthyloxy proline amide was produced.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05668132
Source datasetuspto-grants-1997_09
ORD IDord-f558888bbcde4c5ebc6ebd50fb7c937d
Source noteuspto-grants-1997_09