1-[(5-Fluoro-2,3-dihydrobenzofur-2-yl)carbonyl]-4-benzylpiperazine → 1-[(5-Methoxychrom-3-EN-3-YL)methyl]-4-benzylpiperazine

HRID 1378326Notes

Reaction equation

HRID 1378326 reaction equation
FC1C=CC2OC(C(N3CCN(CC4C=CC=CC=4)CC3)=O)CC=2C=1.Cl.[CH3:27][O:28][C:29]1[CH:38]=[CH:37][CH:36]=[C:35]2[C:30]=1[CH:31]=[C:32]([C:39]([N:41]1[CH2:46][CH2:45][N:44]([CH2:47][C:48]3[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=3)[CH2:43][CH2:42]1)=O)[CH2:33][O:34]2>>[CH3:27][O:28][C:29]1[CH:38]=[CH:37][CH:36]=[C:35]2[C:30]=1[CH:31]=[C:32]([CH2:39][N:41]1[CH2:42][CH2:43][N:44]([CH2:47][C:48]3[CH:53]=[CH:52][CH:51]=[CH:50][CH:49]=3)[CH2:45][CH2:46]1)[CH2:33][O:34]2

Participants

3

Reactant 2

HCID 214722611-[(5-Fluoro-2,3-dihydrobenzofur-2-yl)carbonyl]-4-benzylpiperazineHCID 1317201891-[(5-Methoxychrom-3-en-3-yl)carbonyl]-4-benzylpiperazine hydrochloride

Product 1

HCID 106178521-[(5-Methoxychrom-3-EN-3-YL)methyl]-4-benzylpiperazine

Procedure

By carrying out the preparation as in Example 1, but replacing 1-[(5-fluoro-2,3-dihydrobenzofur-2-yl)carbonyl]-4-benzylpiperazine with the 1-[(5-methoxychrom-3-en-3-yl)carbonyl]-4-benzylpiperazine hydrochloride in the preceding stage, the title product is obtained.

Workup

  1. customthe preparation as in Example 1

Sources & evidence

ORD record
ord-f96ba6d43e6f43e9946e4b0fc17f02bb
Source dataset
uspto-grants-1997_09
Patent number
US05668138

Reaction notes

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