1-[(5-Fluoro-2,3-dihydrobenzofur-2-yl)carbonyl]-4-benzylpiperazine → 1-(2-Phenoxybutyl)-4-benzylpiperazine

HRID 1378328Notes

Reaction equation

HRID 1378328 reaction equation
FC1C=CC2OC(C(N3CCN(CC4C=CC=CC=4)CC3)=O)CC=2C=1.Cl.[O:27]([CH:34]([CH2:50][CH3:51])[C:35]([N:37]1[CH2:42][CH2:41][N:40]([CH2:43][C:44]2[CH:49]=[CH:48][CH:47]=[CH:46][CH:45]=2)[CH2:39][CH2:38]1)=O)[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>>[O:27]([CH:34]([CH2:50][CH3:51])[CH2:35][N:37]1[CH2:38][CH2:39][N:40]([CH2:43][C:44]2[CH:45]=[CH:46][CH:47]=[CH:48][CH:49]=2)[CH2:41][CH2:42]1)[C:28]1[CH:29]=[CH:30][CH:31]=[CH:32][CH:33]=1

Participants

3

Reactant 2

HCID 214722611-[(5-Fluoro-2,3-dihydrobenzofur-2-yl)carbonyl]-4-benzylpiperazineHCID 214722651-(2-Phenoxybutyryl)-4-benzylpiperazine hydrochloride

Product 1

HCID 107583511-(2-Phenoxybutyl)-4-benzylpiperazine

Procedure

By carrying out the preparation as in Example 1, but replacing 1-[(5-fluoro-2,3-dihydrobenzofur-2-yl)carbonyl]-4-benzylpiperazine with the 1-(2-phenoxybutyryl)-4-benzylpiperazine hydrochloride obtained in Example 8, the title product is obtained.

Workup

  1. customthe preparation as in Example 1

Sources & evidence

ORD record
ord-b18cba78e20d44a3b506c084faf365af
Source dataset
uspto-grants-1997_09
Patent number
US05668138

Reaction notes

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