Furfurylamine → HCID 22876890, compound

Participants

Reaction Steps

In substantially the same manner as Working Example 2, furfurylamine (2.91 g) was condensed with Boc-L-phenylalanine (8.75 g) to give N-(Boc-L-phenylalanyl)furfurylamine (9.14 g) (yield 89%). The Boc group of the product was deprotected by using TFA, and 0.43 g of thus-deprotected compound was condensed, in substantially the same manner as Working Example 42, with monoethyl ester of (2S,3S)-N-methylaziridine-2,3-dicarboxylic acid (0.28 g) to give the above-titled compound (Compound 89; 0.23 g) as white crystals (yield 36%).

Provenance & Evidence