4-Chloro-6-methoxypyrimidine → HCID 21753096, compound

Participants

Reaction Steps

7.2 g (0.05 mol ) of 4-chloro-6-methoxypyrimidine and 15.7 g (0.1 mol) of 2-decylamine were heated at 100° C. for 2 hours. The mixture was worked up using a water/methylene chloride mixture, and purification by chromatography (silica gel/ethyl acetate) gave 8.0 g (58.8% of theory) of 4-(2-decylamino)-6-methoxypyrimidine in the form of a yellow oil.

Provenance & Evidence