Chlorosuccinimide → HCID 21753098, compound

Participants

Reaction Steps

4.0 g (0.015 mol) of 4-(2-decylamino)-6-methoxypyrimidine were refluxed for 1 hour together with 2.2 g (0.016 mol) of N-chlorosuccinimide in 25 ml of chloroform. After cooling, the mixture was extracted by stirring with 2N sodium hydroxide solution, and the organic phase was dried and concentrated. 3.8 g (84.3% of theory) of 5-chloro-4-(2-decylamino)-6-methoxypyrimidine were obtained in the form of a yellow oil.

Provenance & Evidence