4-Chloro-5-methoxy-6-(methoxymethyl)pyrimidine → 4-Chloro-5-methylthio-6-methylthiomethylpyrimidine

HRID 1378406Notes

Reaction equation

HRID 1378406 reaction equation
[Cl:1]C1C(OC)=C(COC)N=CN=1.O[C:14]1[C:19]([S:20][CH3:21])=[C:18]([CH2:22][S:23][CH3:24])[N:17]=[CH:16][N:15]=1>>[Cl:1][C:14]1[C:19]([S:20][CH3:21])=[C:18]([CH2:22][S:23][CH3:24])[N:17]=[CH:16][N:15]=1

Participants

3

Reactant 2

HCID 152793504-Chloro-5-methoxy-6-(methoxymethyl)pyrimidineHCID 178503665HCID 178503665, compound

Product 1

HCID 229113124-Chloro-5-methylthio-6-methylthiomethylpyrimidine

Procedure

The preparation was analogous to the synthesis of the starting compound 4-chloro-5-methoxy-6-methoxymethylpyrimidine, using 42 g of 4-hydroxy-5-methylthio-6-methylthiomethylpyrimidine

Sources & evidence

ORD record
ord-f57c486ebb8d48478246057d82dae3c4
Source dataset
uspto-grants-1997_09
Patent number
US05668140

Reaction notes

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