Sodium Bicarbonate → HCID 22911640, compound

Participants

Reaction Conditions

Reaction Steps

A stirred mixture of the product from Step 1 (2.08 g, 0.0112 mol) and EtOH (25 ml), under nitrogen, was treated with stannous chloride dihydrate (12.6 g, 0.056 mol). The mixture was warmed at 75° C. for 30 minutes, cooled and mixed with ice water. This mixture was made alkaline (pH 8-9) with saturated NaHCO3 and extracted with EtOAc. The extract was concentrated to give the titled product which was used without further purification in Step 3.

Provenance & Evidence