1,2-Dimethoxyethane → HCID 178512278, compound

Participants

Reaction Steps

A stirred mixture of the product from Step 2 (0.0112 mol), diphenylcyanocarbonimidate (2.67 g, 0.0112 mol) and ethylene glycol dimethyl ether (25 ml) was kept under nitrogen for 18 hours at 24° C. The mixture was diluted with Et2O (25 ml) and the solid was collected by filtration to give 1.04 g, mp 157°-158° C. of the titled product. The filtrate was purified by silica gel chromatography with 2.5% MeOH--CHcl3 to give 0.39 g of additional product: MS m/z (relative intensity) 299 (M+, 100), 278 (23.5), 266 (24.4), 206 (37.7), 184 (42.6), 172 (68.3), 94 (95.4).

Provenance & Evidence