反应详情

A stirred mixture of 2-chloro-3-nitropyridine (1.00 g, 0.00631 mol) in absolute EtOH (17 ml), under nitrogen, was treated, dropwise during 10 minutes, with 3.86 g (0.0214 mol) of 25% aqueous dimethylamine and kept at ambient temperature (25° C.) for 30 minutes. The mixture was mixed with water and extracted with EtOAc. The extract was washed with water, dried (MgSO4) and concentrated to give 1.05 g of the titled product, a yellow oil.

1. customkept at ambient temperature
2. custom(25° C.)
3. customfor 30 minutes
4. extractionextracted with EtOAc
5. washThe extract was washed with water
6. dry with materialdried (MgSO4)
7. concentrationconcentrated