Methanol → 1-Boc-octahydropyrrolo(3,4-b)pyridine

HRID 137853Notes

Reaction equation

HRID 137853 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]2[N:11]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:12][CH2:13][CH2:14][CH:15]2[CH2:16]1.[CH3:24][OH:25].[OH-:26].[OH-:28].[Pd+2:27]>>[NH:8]1[CH2:9][CH:10]2[N:11]([C:17](=[O:18])[O:19][C:20]([CH3:21])([CH3:22])[CH3:23])[CH2:12][CH2:13][CH2:14][CH:15]2[CH2:16]1

Participants

5

Reactant 4

HCID 887MethanolHCID 961Hydroxide2×HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 190294191-Boc-6-benzyloctahydropyrrolo[3,4-B]pyridine

Product 1

HCID 225622021-Boc-octahydropyrrolo(3,4-b)pyridine

Sources & evidence

ORD record
ord-07b584914e8f4cdcb334045d067559ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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