HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyano-2,6-dichloro-4-methylpyridine → 4-Methyl-3-cyanopyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyano-2,6-dichloro-4-methylpyridine | HCID 70131 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Catalyst | Palladium Chloride | HCID 24290 | — |
| Product | 4-Methyl-3-cyanopyridine | HCID 227806 | — |
Reaction Steps
hydrogenating the 3-cyano-2,6-dichloro-4-methylpyridine produced in b) in the presence of an organic solvent, with an hydrogenation catalyst selected from the group consisting of palladium (II) chloride and 10% Pd/C, at 50 to 150 psi, at a temperature of from 20° C. to 100° C., for 6 to 24 hours, to produce 3-cyano-4-methylpyridine;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05668287 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-aec8da546a4b41c18a5b9393bce6e4e7 |
| Source note | uspto-grants-1997_09 |