2-Aminobenzenesulfonamide → N-(2-sulfamoylphenyl)-2-[[2-[(2-sulfamoylphenyl)carbamoyl]phenyl]disulfanyl]benzamide

Participants

Reaction Conditions

Reaction Steps

This compound was prepared according to the general method of Example 77 using 2,2'-dithiobisbenzoyl chloride (2.00 g, 5.83 mmol) in 50 mL of dichloromethane and 2-aminobenzenesulfonamide (2.00 g, 11.6 mmol) in 16 mL of pyridine. The reaction mixture was stirred for 6 days at 23° C. under nitrogen atmosphere. The crude product was recrystallized from acetonitrile to yield 0.70 g of the title compound, mp 150°-151° C. (dec.).

Provenance & Evidence