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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 1378829Erstellt: 25. Oktober 2026

Tiopronin → 2-[2-[[2-[(4-Sulfamoylphenyl)carbamoyl]phenyl]disulfanyl]propanoylamino]acetic acid

https://huagongshe.com/reaction/1378829

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktTioproninHCID 5483—
Edukt4-(3-Oxo-1,2-benzothiazol-2-yl)benzenesulfonamideHCID 462938—
Produkt2-[2-[[2-[(4-Sulfamoylphenyl)carbamoyl]phenyl]disulfanyl]propanoylamino]acetic acidHCID 648355992,3%

Reaktionsschritte

This compound was prepared according to the method of Example 132 using 0.46 g (1.5 mmol) of 4-(3-oxo-3H-benzo[d]isothiazol-2-yl)benzenesulfonamide and 0.25 g (1.5 mmol) of 2-mercapto-propionylglycine. The product was washed with ether and dried in vacuo to give 0.65 g of the title compound, mp 254°-256° C.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS05668291
Quelldatensatzuspto-grants-1997_09
ORD IDord-42fa9b89d0634314929857e1564f52d6
Quellennotizuspto-grants-1997_09