Acetic Acid → HCID 53861216, compound

HRID 1378915Notes

Reaction equation

HRID 1378915 reaction equation
[N+:1](=[CH2:3])=[N-:2].[CH2:4]([O:6][C:7](=[O:16])[C:8]1[CH:13]=[CH:12][CH:11]=[N:10][C:9]=1[CH:14]=[CH2:15])[CH3:5].C(O)(=O)C>C(OCC)C>[CH2:4]([O:6][C:7](=[O:16])[C:8]1[CH:13]=[CH:12][CH:11]=[N:10][C:9]=1[CH:14]1[CH2:15][CH2:3][N:1]=[N:2]1)[CH3:5]

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 9550DiazomethaneHCID 54555908HCID 54555908, compound

Product 1

HCID 53861216HCID 53861216, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

An excess of diazomethane in diethylether is added to 3.35 g of 2-vinylnicotinic acid ethyl ester and stirred at -10° overnight. Acetic acid is added until gas evolution ceases and the solvent is removed by evaporation under vacuum.

Workup

  1. customthe solvent is removed by evaporation under vacuum

Sources & evidence

ORD record
ord-13f0901ddf174b75934d1967c01d8443
Source dataset
uspto-grants-1997_09
Patent number
US05670456

Reaction notes

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