HCID 178418287, compound → HCID 178520954, compound

Participants

Reaction Steps

41.2 g (191 mmol) of pyridinium chlorochromate are added in several portions to a suspension of trans-1,4-bis(hydroxymethyl)cyclohexane (13.8 g, 96 mmol) in 300 ml of dichloromethane. After 1 h 30 min of stirring at room temperature, a further 4 g of pyridinium chlorochromate are added and stirring is continued for 15 min. The reaction medium is filtered through Celite and the filtrate is passed through silica. After evaporation, an oil is obtained, which is used in Stage B without further purification.

Provenance & Evidence