Aniline → HCID 22909003, compound

HRID 1378983Notes

Reaction equation

HRID 1378983 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([S:31](O)(=[O:33])=[O:32])[C:6](=[CH:27][C:28]=1[O:29][CH3:30])/[CH:7]=[CH:8]/[C:9]1[N:17]([CH3:18])[C:16]2[C:15](=[O:19])[N:14]([CH2:20][CH2:21][CH3:22])[C:13](=[O:23])[N:12]([CH2:24][CH2:25][CH3:26])[C:11]=2[N:10]=1.[NH2:35][C:36]1[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1>>[C:36]1([NH:35][S:31]([C:5]2[C:6](=[CH:27][C:28]([O:29][CH3:30])=[C:3]([O:2][CH3:1])[CH:4]=2)/[CH:7]=[CH:8]/[C:9]2[N:17]([CH3:18])[C:16]3[C:15](=[O:19])[N:14]([CH2:20][CH2:21][CH3:22])[C:13](=[O:23])[N:12]([CH2:24][CH2:25][CH3:26])[C:11]=3[N:10]=2)(=[O:32])=[O:33])[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=1

Participants

3

Reactant 2

HCID 6115AnilineHCID 22909004HCID 22909004, compound

Product 1

HCID 22909003HCID 22909003, compoundYield 23.5%

Procedure

Substantially the same procedure as in Example 2 was repeated using 1.00 g (1.96 mmol) of Compound 1 obtained in Example 1 and 1.85 ml (20.3 mmol) of aniline. The resulting crude crystals were recrystallized from toluene to give 261 mg (yield 23%) of Compound 10 as a pale yellow powder.

Workup

  1. customThe resulting crude crystals were recrystallized from toluene

Sources & evidence

ORD record
ord-53d1e8e00fe14f5c86091272cd893cb6
Source dataset
uspto-grants-1997_09
Patent number
US05670498

Reaction notes

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