HCID 22909495, compound → HCID 22909437, compound

HRID 1379040Notes

Reaction equation

HRID 1379040 reaction equation
C[O:2][C:3]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[NH:10][CH:9]=[C:8]2[CH:14]1[CH2:19][CH2:18][N:17]([CH2:20][CH2:21][N:22]2[C:31](=[O:32])[C:30]3[CH:33]=[CH:34][CH:35]=[C:28]4[C:29]=3[C:24](=[CH:25][CH:26]=[CH:27]4)[C:23]2=[O:36])[CH2:16][CH2:15]1)=[O:4]>[OH-].[K+]>[C:3]([C:5]1[CH:6]=[C:7]2[C:11](=[CH:12][CH:13]=1)[NH:10][CH:9]=[C:8]2[CH:14]1[CH2:15][CH2:16][N:17]([CH2:20][CH2:21][N:22]2[C:23](=[O:36])[C:24]3[CH:25]=[CH:26][CH:27]=[C:28]4[C:29]=3[C:30](=[CH:33][CH:34]=[CH:35]4)[C:31]2=[O:32])[CH2:18][CH2:19]1)([OH:4])=[O:2]

Participants

3

Reactant 1

HCID 22909495HCID 22909495, compound

Product 1

HCID 22909437HCID 22909437, compound

Reagents, catalysts & solvents 1

HCID 14797Potassium HydroxideSolvent

Procedure

0.8 g of 2-[2-(4-(5-methoxycarbonyl-3-indolyl)piperidino)ethyl]-2,3-dihydro-1H-benz[de]isoquinoline-1,3-dione[obtainable according to Example 1] is heated with 100 ml of 2N ethanolic KOH for 0.5 hours and worked up in the customary manner, and 2-[2-(4-(5-carboxy-3-indolyl)piperidino)ethyl]-2,3-dihydro-1H-benz[de]isoquinoline-1,3-dione is obtained.

Sources & evidence

ORD record
ord-c4b98b66fc4f48308bcff2589f09073a
Source dataset
uspto-grants-1997_09
Patent number
US05670511

Reaction notes

Loading…