2-Dimethylaminopyridine → HCID 22909777, compound

Participants

Reaction Steps

0.10 g (0.23 mmol) of N-{3-(3,4-dimethylphenyl)propyl}-4-(2-bromoethoxy)-3-methoxyphenylacetamide obtained in Step 5 of Example 3, 0.16 g (2.3 mmol) of pyrrolidine and a catalytic amount of dimethylaminopyridine were dissolved in 10 ml of benzene, and the mixture was refluxed for 5 hours. After removing the solvent under a reduced pressure, the residue was subjected to silica gel column chromatography (eluent: ethyl acetate:hexane=1:1) to obtain the title compound.

Provenance & Evidence