HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Chloro-N,N-dimethylbenzamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Dimethylamine | HCID 674 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 4-Chlorobenzoyl chloride | HCID 8501 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 4-Chloro-N,N-dimethylbenzamide | HCID 84180 | — |
Reaction Steps
4-Chloro-N,N-dimethylbenzamide is prepared by reacting 4-chlorobenzoyl chloride with dimethylamine in toluene with some pyridine (1 mol equivalent per acid chloride) to trap the HCl that is evolved. After aqueous extraction of the pyridinium salt and any excess starting materials, the product is crystallized from the toluene solution.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05670564 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-ee0d71690e4d4c0b8ab23eb1c1ba4511 |
| Source note | uspto-grants-1997_09 |