HuagongsheHuagongshe Chemistry Print Report · For research reference only
methyl (4S,5R)-4-benzyl-2-oxo-oxazolidine-5-carboxylate → Methyl (4S,5R)-4-cyclohexylmethyl-2-oxo-oxazolidine-5-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | methyl (4S,5R)-4-benzyl-2-oxo-oxazolidine-5-carboxylate | HCID 9813432 | — |
| Reactant | methyl (4S,5S)-4-cyclohexylmethyl-2-oxo-oxazolidine-5-carboxylate | HCID 57299894 | — |
| Product | Methyl (4S,5R)-4-cyclohexylmethyl-2-oxo-oxazolidine-5-carboxylate | HCID 15689688 | 95% |
Reaction Steps
For the manufacture of the aforementioned compound, methyl (4S,5S)-4-cyclohexylmethyl-2-oxo-oxazolidine-5-carboxylate, obtainable by hydrogenating methyl (4S,5R)-4-benzyl-2-oxo-oxazolidine-5-carboxylate, is reacted under the conditions given in Example 1. Methyl (4S,5R)-4-cyclohexylmethyl-2-oxo-oxazolidine-5-carboxylate is obtained in a yield of about 95%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05670653 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-a5dbed221929437d8d4ed2a7ca3992b5 |
| Source note | uspto-grants-1997_09 |