Benzenepropanal → HCID 14249550, compound

HRID 1379351Notes

Reaction equation

HRID 1379351 reaction equation
Br[C:2]([F:9])([F:8])[C:3]([O:5][CH2:6][CH3:7])=[O:4].[CH:10](=[O:19])[CH2:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>>[F:8][C:2]([F:9])([CH:10]([OH:19])[CH2:11][CH2:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1)[C:3]([O:5][CH2:6][CH3:7])=[O:4]

Participants

3

Reactant 2

HCID 7707BenzenepropanalHCID 69585Ethyl bromodifluoroacetate

Product 1

HCID 14249550HCID 14249550, compound

Procedure

According to the procedure of Thaisrivongs et. al. (J. Med. Chem., 1986, 29, 2080), ethyl bromodifluoroacetate was condensed with hydrocinnamaldehyde to give the desired compound.

Sources & evidence

ORD record
ord-6a677e6a45364cb086075017c52e8d47
Source dataset
uspto-grants-1997_09
Patent number
US05670675

Reaction notes

Loading…