HuagongsheHuagongshe Chemistry Print Report · For research reference only
Boc-L-Valine → n-Boc-valinyl-valine benzyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Boc-L-Valine | HCID 83693 | — |
| Reactant | O-benzyl-L-valine toluene-p-sulphonate | HCID 11567066 | — |
| Product | n-Boc-valinyl-valine benzyl ester | HCID 12854597 | — |
Reaction Steps
Boc-Val-OH (2.86 g, 13.2 mmol) was coupled to valine benzyl ester p-toluenesulfonate (5.0 g, 13.2 mmol) using the procedure of Example 55 to give 5.41 g, (100%) of the desired product (RF 0.15; 20% ethyl acetate in hexane) as a colorless gum. Mass spectrum (M+H)+ =407.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05670675 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-9822edb91e4347299c7822f145c61579 |
| Source note | uspto-grants-1997_09 |