HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(((Phenylmethoxy)carbonyl)amino)hexanoic acid → 2(t-Butyloxycarbonylamino)-4-((6-(Cbz-amino)hexanoyl)amino)-1,5-diphenyl-3-hydroxypentane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(((Phenylmethoxy)carbonyl)amino)hexanoic acid | HCID 74758 | — |
| Reactant | 4-Amino-2-(t-butyloxycarbonylamino)-1,5-diphenyl-3-hydroxypentane | HCID 14704377 | — |
| Product | 2(t-Butyloxycarbonylamino)-4-((6-(Cbz-amino)hexanoyl)amino)-1,5-diphenyl-3-hydroxypentane | HCID 22910256 | — |
Reaction Steps
N-(6-(Benzyloxycarbonylamino)hexanoic acid was coupled to the resultant compound of Example 11 using the mixed anhydride procedure of Example 54A to give the desired compound after silica gel chromatography using 75% ethyl acetate in chloroform.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05670675 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-1df14b3e4a7d45fdb961c639ca2b63b9 |
| Source note | uspto-grants-1997_09 |