Methanol → HCID 3011035, compound

Participants

Reaction Steps

Picolinic acid was coupled to the resultant compound of Example 173 using the carbodiimide coupling procedure described in Example 55 to provide after silica gel chromatography using a gradient of 5-10% methanol in chloroform, the desired compound (Rf 0.16, 10% methanol in chloroform) as a white solid, m.p. 167°-171° C., in 61% yield. Mass spectrum: (M+H)+ =709.

Provenance & Evidence