Quinaldic Acid → HCID 15704317, compound

HRID 1379416Notes

Reaction equation

HRID 1379416 reaction equation
[C:1]([OH:13])(=O)[C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[NH2:14][C@H:15]([C:19]([NH:21][C@H:22]([C@@H:30]([OH:49])[C@H:31]([OH:48])[C@@H:32]([NH:40][C:41](=[O:47])[C@H:42]([CH:44]([CH3:46])[CH3:45])[NH2:43])[CH2:33][C:34]1[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=1)[CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)=[O:20])[CH:16]([CH3:18])[CH3:17].N=[C:51]=[NH:52]>>[N:52]1[C:51]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[CH:10]=[CH:11][C:2]=1[C:1]([NH:14][C@H:15]([C:19]([NH:21][C@H:22]([C@@H:30]([OH:49])[C@H:31]([OH:48])[C@@H:32]([NH:40][C:41](=[O:47])[C@H:42]([CH:44]([CH3:45])[CH3:46])[NH:43][C:1]([C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1)=[O:13])[CH2:33][C:34]1[CH:35]=[CH:36][CH:37]=[CH:38][CH:39]=1)[CH2:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][CH:25]=1)=[O:20])[CH:16]([CH3:18])[CH3:17])=[O:13]

Participants

4

Reactant 3

HCID 7124Quinaldic AcidHCID 160435CarbodiimideHCID 10368652HCID 10368652, compound

Product 1

HCID 15704317HCID 15704317, compound

Procedure

Quinaldic acid was coupled to the resultant compound of Example 173 using the carbodiimide coupling procedure of Example 55 to provide the desired compound.

Sources & evidence

ORD record
ord-ed618befd11f474c8f35555635179cbb
Source dataset
uspto-grants-1997_09
Patent number
US05670675

Reaction notes

Loading…