HCID 12593610, compound → HCID 178457584, compound

Participants

Reaction Steps

There were dissolved 4.0 g (0.0106 mol) of N-[4-[3-(piperidinomethyl)phenoxy]-cis-2-butenyl]-2-(2-aminoethylthio)acetamide and 2.01 g (0.0159 mol) of methyl N-cyanopropioimidate in 40 ml of acetonitrile, and after reflux with heating for 18 hours the solvent was removed under reduced pressure. The residue was purified by silica gel column chromatography (chloroform:ethanol=10:1) to give 0.69 g of the titled compound as oily matter.

Provenance & Evidence