HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → HCID 54016786, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Benzene, (3-chloro-1-propenyl)- | HCID 94242 | — |
| Reactant | 1-(3,8-Diazabicyclo[3.2.1]octan-8-yl)ethan-1-one | HCID 12430602 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | HCID 54016786 | HCID 54016786 | — |
Reaction Steps
N8 -acetyl-3,8-diazabicyclo[3.2.1]octane was reacted with equimolar amounts of cinnamyl chloride, in the presence of potassium carbonate in acetone under reflux, checking the reaction by thin layer chromatography (TLC). When the reaction was completed, the inorganic salt was filtered off and the filtrate evaporated to dryness. The residue was purified by chromatography (1:1 CHCl3 /Ethyl acetate). N8 -Acetyl-N3 -cinnamyl-3,8-diazabicyclo[3.2.1]octane was obtained, the elementary analysis being in accordance with the desired compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05672601 |
| Source dataset | uspto-grants-1997_09 |
| ORD ID | ord-07fe05ffbee24497a967f54dc0d557c1 |
| Source note | uspto-grants-1997_09 |