HRID1379768

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(NC(=O)c4ccccc4)nc3=O)C[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

HCID2724490

Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-

C37H35N3O7

结构：CC(C)C(=O)Nc1nc2c(ncn2[C@H]2C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO)O2)c(=O)[nH]1

HCID136483518

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](n2ccc(NC(=O)c3ccccc3)nc2=O)O[C@@H]1CO

HCID10647001

N-[1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

C22H31N3O5Si

PROCEDURE

实验过程

This compound was prepared from N4 -benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine by the same procedure used for the preparation of 3'-O-t-butyldimethylsilyl-N2 -isobutyryl-2'-deoxyguanosine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-f240df17c5f44afdb69d502da64626c0
来源数据集: uspto-grants-1997_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05672697
来源说明: uspto-grants-1997_09

反应 SMILES

[C:1]([NH:9][C:10]1[CH:46]=[CH:45][N:13]([C@@H:14]2[O:44][C@H:18]([CH2:19][O:20]C(C3C=CC=CC=3)(C3C=CC(OC)=CC=3)C3C=CC(OC)=CC=3)[C@@H:16]([OH:17])[CH2:15]2)[C:12](=[O:47])[N:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Si:48](O[C@@H]1[C@@H](CO)O[C@@H](N2C3N=C(NC(=O)C(C)C)NC(=O)C=3N=C2)C1)([C:51]([CH3:54])([CH3:53])[CH3:52])([CH3:50])[CH3:49]>>[Si:48]([O:17][C@@H:16]1[C@@H:18]([CH2:19][OH:20])[O:44][C@@H:14]([N:13]2[CH:45]=[CH:46][C:10]([NH:9][C:1](=[O:8])[C:2]3[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=3)=[N:11][C:12]2=[O:47])[CH2:15]1)([C:51]([CH3:54])([CH3:53])[CH3:52])([CH3:50])[CH3:49]