HRID1379769

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(NC(=O)c5ccccc5)ncnc43)C[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

HCID2724489

Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-

C38H35N5O6

结构：CC(C)C(=O)Nc1nc2c(ncn2[C@H]2C[C@H](O[Si](C)(C)C(C)(C)C)[C@@H](CO)O2)c(=O)[nH]1

HCID136483518

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](n2cnc3c(NC(=O)c4ccccc4)ncnc32)O[C@@H]1CO

HCID11590906

N-[9-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]purin-6-yl]benzamide

C23H31N5O4Si

PROCEDURE

实验过程

This compound was prepared from N6 -benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine by the same procedure used for the preparation of 3'-O-t-butyldimethylsilyl-N2 -isobutyryl-2'-deoxyguanosine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-6531972cfaa34cf09d986918d36026e6
来源数据集: uspto-grants-1997_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05672697
来源说明: uspto-grants-1997_09

反应 SMILES

[C:1]([NH:9][C:10]1[C:11]2[N:12]=[CH:13][N:14]([C:46]=2[N:47]=[CH:48][N:49]=1)[C@@H:15]1[O:45][C@H:19]([CH2:20][O:21]C(C2C=CC=CC=2)(C2C=CC(OC)=CC=2)C2C=CC(OC)=CC=2)[C@@H:17]([OH:18])[CH2:16]1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Si:50](O[C@@H]1[C@@H](CO)O[C@@H](N2C3N=C(NC(=O)C(C)C)NC(=O)C=3N=C2)C1)([C:53]([CH3:56])([CH3:55])[CH3:54])([CH3:52])[CH3:51]>>[Si:50]([O:18][C@@H:17]1[C@@H:19]([CH2:20][OH:21])[O:45][C@@H:15]([N:14]2[C:46]3[N:47]=[CH:48][N:49]=[C:10]([NH:9][C:1](=[O:8])[C:2]4[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=4)[C:11]=3[N:12]=[CH:13]2)[CH2:16]1)([C:53]([CH3:56])([CH3:55])[CH3:54])([CH3:52])[CH3:51]