HRID1379773

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(NC(=O)c4ccccc4)nc3=O)C[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

HCID2724490

Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-

C37H35N3O7

结构：O=C(Nc1ccn([C@@H]2O[C@H](CO)[C@@H](O)[C@@H]2F)c(=O)n1)c1ccccc1

HCID54266479

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(NC(=O)c4ccccc4)nc3=O)[C@@H](F)[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

HCID70700565

4-Benzamido-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl}pyrimidin-2(1H)-one

C37H34FN3O7

PROCEDURE

实验过程

This compound is prepared from 1-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-N4 -benzoylcytosine by the same procedure used for the preparation of N4 -benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxycytidine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ddf24c9cfde04cab8577c84c8f8c05f3
来源数据集: uspto-grants-1997_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05672697
来源说明: uspto-grants-1997_09

反应 SMILES

[F:1][C@H:2]1[C@H:6]([OH:7])[C@@H:5]([CH2:8][OH:9])[O:4][C@H:3]1[N:10]1[CH:25]=[CH:24][C:14]([NH:15][C:16](=[O:23])[C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[N:13][C:11]1=[O:12].C(NC1C=CN([C@@H]2O[C@H](CO[C:46]([C:63]3[CH:68]=[CH:67][CH:66]=[CH:65][CH:64]=3)([C:55]3[CH:60]=[CH:59][C:58]([O:61][CH3:62])=[CH:57][CH:56]=3)[C:47]3[CH:52]=[CH:51][C:50]([O:53][CH3:54])=[CH:49][CH:48]=3)[C@@H](O)C2)C(=O)N=1)(=O)C1C=CC=CC=1>>[CH3:62][O:61][C:58]1[CH:57]=[CH:56][C:55]([C:46]([O:9][CH2:8][C@H:5]2[O:4][C@@H:3]([N:10]3[CH:25]=[CH:24][C:14]([NH:15][C:16](=[O:23])[C:17]4[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=4)=[N:13][C:11]3=[O:12])[C@@H:2]([F:1])[C@@H:6]2[OH:7])([C:63]2[CH:64]=[CH:65][CH:66]=[CH:67][CH:68]=2)[C:47]2[CH:52]=[CH:51][C:50]([O:53][CH3:54])=[CH:49][CH:48]=2)=[CH:60][CH:59]=1