HRID1379774

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(NC(=O)c5ccccc5)ncnc43)C[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

HCID2724489

Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-

C38H35N5O6

结构：O=C(Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F)c1ccccc1

HCID53883372

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(NC(=O)c5ccccc5)ncnc43)[C@@H](F)[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

HCID67563215

未命名化合物

PROCEDURE

实验过程

This compound is prepared from 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-N6 -benzoyladenine by the same procedure used for the preparation of N6 -benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ab7517ff13614891ac7266d8fd6a5e5b
来源数据集: uspto-grants-1997_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05672697
来源说明: uspto-grants-1997_09

反应 SMILES

[F:1][C@H:2]1[C@H:6]([OH:7])[C@@H:5]([CH2:8][OH:9])[O:4][C@H:3]1[N:10]1[CH:18]=[N:17][C:16]2[C:11]1=[N:12][CH:13]=[N:14][C:15]=2[NH:19][C:20](=[O:27])[C:21]1[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=1.C(NC1C2N=CN(C=2N=CN=1)[C@@H]1O[C@H](CO[C:49]([C:66]2[CH:71]=[CH:70][CH:69]=[CH:68][CH:67]=2)([C:58]2[CH:63]=[CH:62][C:61]([O:64][CH3:65])=[CH:60][CH:59]=2)[C:50]2[CH:55]=[CH:54][C:53]([O:56][CH3:57])=[CH:52][CH:51]=2)[C@@H](O)C1)(=O)C1C=CC=CC=1>>[CH3:65][O:64][C:61]1[CH:60]=[CH:59][C:58]([C:49]([O:9][CH2:8][C@H:5]2[O:4][C@@H:3]([N:10]3[CH:18]=[N:17][C:16]4[C:11]3=[N:12][CH:13]=[N:14][C:15]=4[NH:19][C:20](=[O:27])[C:21]3[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=3)[C@@H:2]([F:1])[C@@H:6]2[OH:7])([C:66]2[CH:67]=[CH:68][CH:69]=[CH:70][CH:71]=2)[C:50]2[CH:55]=[CH:54][C:53]([O:56][CH3:57])=[CH:52][CH:51]=2)=[CH:63][CH:62]=1