HRID1379776

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(C)(C)[Si](C)(C)O[C@H]1C[C@H](n2ccc(NC(=O)c3ccccc3)nc2=O)O[C@@H]1CO

HCID10647001

N-[1-[(2R,4S,5R)-4-[tert-butyl(dimethyl)silyl]oxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]benzamide

C22H31N3O5Si

结构：COc1ccc(C(OC[C@H]2O[C@@H](n3ccc(NC(=O)c4ccccc4)nc3=O)[C@@H](F)[C@@H]2O)(c2ccccc2)c2ccc(OC)cc2)cc1

HCID70700565

4-Benzamido-1-{5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-2-fluoro-beta-D-arabinofuranosyl}pyrimidin-2(1H)-one

C37H34FN3O7

PRODUCTS

生成物

结构：CC(C)(C)[Si](C)(C)O[C@H]1[C@H](F)[C@H](n2ccc(NC(=O)c3ccccc3)nc2=O)O[C@@H]1CO

HCID131720217

未命名化合物

PROCEDURE

实验过程

This compound is prepared from 1-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-2-fluoro-β-D-arabinofuranosyl]-N4 -benzoylcytosine by the same procedure used for the preparation of 3'-O-t-butyldimethylsilyl-N4 -benzoyl-2'-deoxycytidine.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-62b69565f3524e9b968e409cac5fa69d
来源数据集: uspto-grants-1997_09
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05672697
来源说明: uspto-grants-1997_09

反应 SMILES

COC1C=CC(C([O:22][CH2:23][C@H:24]2[O:28][C@@H:27]([N:29]3[CH:44]=[CH:43][C:33]([NH:34][C:35](=[O:42])[C:36]4[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=4)=[N:32][C:30]3=[O:31])[C@@H:26]([F:45])[C@@H:25]2[OH:46])(C2C=CC=CC=2)C2C=CC(OC)=CC=2)=CC=1.[Si:49](O[C@@H]1[C@@H](CO)O[C@@H](N2C=CC(NC(=O)C3C=CC=CC=3)=NC2=O)C1)([C:52]([CH3:55])([CH3:54])[CH3:53])([CH3:51])[CH3:50]>>[Si:49]([O:46][C@@H:25]1[C@@H:24]([CH2:23][OH:22])[O:28][C@@H:27]([N:29]2[CH:44]=[CH:43][C:33]([NH:34][C:35](=[O:42])[C:36]3[CH:37]=[CH:38][CH:39]=[CH:40][CH:41]=3)=[N:32][C:30]2=[O:31])[C@H:26]1[F:45])([C:52]([CH3:55])([CH3:54])[CH3:53])([CH3:51])[CH3:50]